A young South African boy from the Johannesburg ghetto named Tsotsi, meaning Gangster, leaves home as a child to get away from his helpless parents. Now a teenage thug, Tsotsi finds a baby in the back seat of a car he's just stolen. He decides that it is his responsibility to care for the infant and in the process learns that maybe the criminal life isn’t the best way.

A hot-shot journalist is swept up in a movement to challenge Apartheid in 1950s South Africa.