In 19th century Baltimore, Isabel Porter, a girl stricken with grief from her parents' untimely death, voluntarily checks herself into the Rosewood Institute. Subjected to bizarre and increasingly violent pseudo-scientific experiments in personality modification, brainwashing and mind control, she must escape the clutches of the Rosewood and exact her revenge, or else be forever lost.

"Respire" is a short coming-of-age drama that follows three characters through an intriguing night that goes south when one of the girls is drugged and her best friend, who is intoxicated, must problem-solve in order to help her.