Returning from Mecca, Darwis changes his name to Ahmad Dahlan as he is disturbed by the trend of Islamic laws in his society; that borders on heresy, Syrik (polytheism), and Bid’ah (wrong innovation). Using a compass, he proves that the direction of Qibla (that points to Mecca), in the Great Mosque of Kauman is wrong. The discovery angers every Kyai (Islamic experts), especially the head of the Great Mosque of Kauman, Kyai Penghulu Cholil Kamaludiningrat. Dahlan, who studied in Mecca for five years, is seen as a rebel upstart. Since the proposal of changing the direction of Qibla is rejected, Dahlan starts a movement calling for the change. On his first sermon as a preacher, Dahlan criticizes the habits of residents in his village in Yogyakarta: "In a prayer, only a sincere and patient heart is needed, it requires no Kyais, money, let alone offerings". As a result, Dahlan gets a hostile reception.

Cinta Paling Agung is about Khairi (Aaron Aziz) and Amyza (Siti Saleha) who has been married for almost ten years and had a daughter, Hanna. However, their marriage was unhappy and increasingly problematic. Khairi then falls in love with a woman named Dewi (Zaskya) . Because of Dewi, Khairi could decide to divorce his wife. Amyza was shocked by the decision and then decide to agree provided each morning Khairi have to carry her every day for 30 days.

Fahri attracted many women, including Maria, Nurul, and Naora. They hide their feelings until Fahri's marriage with Aisha which broke their hearts.

A girls friendship with hijab. Three married women and a friend who is still single secretly started a hijab business without her husband knowing.

Ardan's life is very simple, but he's a fighter, patient, perseverance and always sincere. Whatever trials upon him, his faith to bring the family out of the poverty remains.

Pras and Arini's love was destroyed in Arini's eyes when he chose to marry Meirose secretly. Their ideal marriage collapsed instantly.

As Jovial does everything he can to prove his love for Alexandra, his brother Andovi records his comical failures and uploads them on his social media channel. Andovi's success constantly comes at Jovial's expense as they both become famous.

Madrim, a porter, feels that he is the most unfortunate man on earth. His friend, Kadir, a mushola (an Islamic prayer place) keeper suggests that he pray diligently. Madrim follows this advice but his fate does not change. Madrim then thinks of robbery. In his prayers, he threatens God that if his wish is not fulfilled within three days, he will turn to the devil. On the third day, lightning strikes Madrim and he falls unconscious.

In a story of interconnected lives, three families of different religious faiths navigate conflicting beliefs, hardships, and other struggles.