G.I. Joe: The Revenge of Cobra is the second G.I. Joe miniseries based on the successful Hasbro Toys and Marvel Comics property. Using a laser core stolen from G.I.Joe, Cobra activates the Weather Dominator, an incredible weapon which controls the forces of Nature itself, Cobra Commander targets Washington for destruction, but the Joe team repels the attack and the Weather Dominator explodes into three parts setting off a chain reaction of natural disasters around the world. Can G.I.Joe recover the Weather Dominator in time to beat Cobra and save the world. It aired in 1984 and most of the 1984 and even some 1985 products are given plenty of screen time. Like the first miniseries, A Real American Hero, The Revenge of Cobra was written by Ron Friedman who created the series for television, and wrote all four miniseries.

G.I. Joe faces a new enemy as an ancient society of snake people known as Cobra-La try to forcefully take back the earth from those who drove them underground eons ago.

After yet another defeat inflicted by G.I. Joe, the immediate subordinates of Cobra's leader, Cobra Commander, have finally come to the end of their patience with his apparent incompetence and his inability to achieve real victories. The leader of the research and interrogations wing, Dr. Mindbender, receives a dream showing the solution. His plan is to collect the genetic material of great warriors and military leaders to create a composite clone that would be the perfect leader for Cobra. Now they set out to put this scheme into motion, and G.I. Joe has very little time to learn of this plot before Cobra becomes that much more a dire threat to the world.

Zartan and Cobra seize the Delta Space Station and destroy G.I. Joe headquarters. Shipwreck and Snake Eyes are lost behind enemy lines while Cobra Commander reveals his plan to deprive the world of electricity.