Scientists have developed a drug that can make women beautiful, but due to the uncontrolled side effects of biotechnology, it has evolved into an infectious virus called the "beautiful girl virus." The infected person will forcibly kiss other healthy humans to spread the virus, and the infected person will become the details regardless of the original gender and appearance.

A strange old man tasks the adventure trio Wu Xie, Zhang Qiling, and Wang Pangzi to investigate the mysterious "misty immortals" in the southwestern mountains. Deep in the mountain, they uncover an ancient black-gold coffin and realize they’ve been entangled in a grand conspiracy.

The border is treacherous, and the dissident guards are plotting to divide and rebel! After the battle of Shule, Geng Gong (Xie Miao) was ordered to patrol the western region with his 13 generals and was sacked and killed by bandits near Mengcheng. The story begins with the death of Geng Gong.