France, 15th century. A strange evil has taken hold of the inhabitants of a village, causing insomnia, tremors, and hallucinations. Little Wolf arrives in the village with his parents. His father, the executioner Simon, has been called in to help Toussaint, the local executioner who has also been affected by the disease.

This film is an homage to the Gaza Strip and to the possibility of hope beyond hopelessness. Ouroboros, the symbol of the snake eating its tail, is both end and beginning: death as regeneration. A 74-minute experimental narrative film that turns the destruction of Gaza into a story of heartbreak, Ouroboros asks what it means to be human when humanity has failed. Taking the form of a love story, the film's central character is Diego Marcon, a man who embarks on a circular journey to shed his pain only to experience it, again and again. In the course of a single day, his travel fuses together Native American territories, the ancient Italian city of Matera, a castle in Brittany, and the ruins of the Gaza Strip into a single landscape.

When a wolf kills sheep herds and motivates huge nocturnal hunts, Antoine returns with his girlfriend Diane in the mining town where he grew up. In order to facilitate the reconversion of the mine, he must expropriate Isère, his recalcitrant childhood friend.