Kim Seon-ae works at the AIDS Research Laboratory, Jang Mi-joo works at a nooky establishment and Han Seong-ae is a psychiatrist. Seong-ae talks to single men about sex and is responsible for her friend Seon-ae's hypnotic treatment. One day, Seong-ae hears something shocking about AIDS during therapy... Seon-ae shudders at the mention of men and doesn't want anything to do with them. Seong-ae tries to treat this woman hooks her up with Jae-san at a club. Mi-joo is pressured to perform oral sex in order to marry Jae-seon as she is bad-off and survives every day by working at the sexual establishment. Mi-joo had lied about her family being well-off and when Jae-san asked to visit her home, she became surprised. She calls Seon-ae who she doesn't usually call and asks her for a favor. Seon-ae meets a man for the first time at a club!!! Mi-joo can't refuse anything her boyfriend asks for! Same goes for Park Jae-san. The three of them are out for trouble...

Miss Sin (Min Song-ah), Miss Go (Han Gyoo-ri), Miss Choi (Yoo Seon-yeong) and Miss Lee (Tae Woo) are women who used to be hot in Kangnam, Seoul. They are sick of the prostitution world and leave for their hometwon in Jinan. They open a coffee shop called "Miss Call" and swoon all the men in the area. People start coming in from afar to see them after hearing about them on the Internet. But one day, a madame they used to work for visits their coffee shop...

Three friends in their twenties struggle with their attitudes towards men. Hyo Rin believes in free sex, Yi An believes in keeping her virginity, and Yoo Jin is popular amongst the men, but after having been raped when she was young, she likes women more. The three go to Kangwondo on a trip and seek their sexual fantasies, releasing their inner desires.