Cops go under cover to track down a Mafia drug kingpin who has re-entered the country to sell "junk" to the prostitutes and "hopheads" on Bourbon Street. Edited from TV series N.O.P.D.

A medical examiner discovers that an innocent shooting victim in a robbery died of bubonic plague. With only 48 hours to find the killer, who is now a ticking time bomb threatening the entire city, a grisly manhunt through the seamy underworld of the New Orleans Waterfront is underway.