A fugitive, dangerous madman reaches an English village where he confronts his former partner who left him for dead in the jungle after their discovery of a diamond mine. When the former partner also claims to have since lost the mine and all its wealth, which he took all for himself, and though the partner is still living in a state of luxury , the madman takes up an offer from a crazed scientist to make him invisible, something the scientist has already done with experimental animals, so that he can take revenge.

Assistant District Attorney Jeffery Powell has just sent an innocent man to prison for the murder of a gambler. Powell is in love with, Marion Courtney, but he's unaware that Marion is the sister of the innocent man he sent to prison. Marion gets herself committed to a women's prison to get proof from inmate, Evelyn 'Duchess' Thane, that her brother is innocent. Powell learns of Marion's plight and believes she's in love with the man he sent to prison.

Songwriter Gus Kahn fights to make his name, then has to fight again to survive the Depression.

Gildersleeve has jury duty.

Expecting the usual loss, a boxing manager takes bribes from a betting gangster without telling his fighter.

Mr. Bowser believes that he'll be able to clean the house better than his wife can.

Five O. Henry stories, each separate. The primary one from the critics' acclaim was "The Cop and the Anthem". Soapy tells fellow bum Horace that he is going to get arrested so he can spend the winter in a nice jail cell. He fails. He can't even accost a woman; she turns out to be a streetwalker. The other stories are "The Clarion Call", "The Last Leaf", "The Ransom of Red Chief", and "The Gift of the Magi".

A gambler faces deportation when he gets mixed up with murder.

Frenchie Fontaine sells her successful business in New Orleans to come West. Her reason? Find the men who killed her father, Frank Dawson. But she only knows one of the two who did and she's determined to find out the other.

When Ivy, an Edwardian belle, begins to like Miles, a wealthy gentleman, she is unsure of what to do with her husband, Jervis, or her lover, Dr. Roger. She then hatches a plan to get rid of them both.