Daniel Robin has become mixed up with a band of criminals known as "the 13," and is shot when he refuses to do their bidding. His daughter Ruth, brought home from boarding school, reaches his bedside before he expires. He tells her that she will be given thirteen keys. Instructions will be provided with each key and, if she follows the instructions, she will eventually fully learn of her birthright. Many adventures then follow as Ruth attempts to solve the puzzle of each key and establish her true birthright.

A publicist for a racy burlesque troupe romances the daughter of the head of The Purity League, an organization that wishes to see such shows banned.

The daughter of an American diplomat is forced to spy for Mexican revolutionaries.

Disinherited by his father, Jeffrey Masters leaves his New York home and amasses a fortune in Texas cattle country. When his younger brother Bob marries Elvine Van Blooren, known as Effie, contrary to his father's wishes, he also is disinherited. Like Jeffrey, Bob goes West, but turns to rustling and becomes the leader of a gang. When Effie, who knows nothing about Bob's involvement with the gang, learns about their hiding place, she informs on them for a much needed $10,000 reward.