Three astronauts crash land on an Earth-like planet after returning from a 7-year long expedition to Ganymede. The planet however is populated by murderous psychopaths who kill two of the astronauts right away. The third, Roger Corman, flees to the alien countryside where he decides to begin a violent quest to find out the truth behind his mission.

Told in Documentary form, the film depicts a group of five British film critics and politicians who venture off into the West Virginian wilderness in search of the "Tony Blair Witch" which may or may not be related to British Prime Minister Tony Blair.