Madrid, the beginning of the century. One day, the police inspector Santos Trinidad coming home very drunk, is involved in a triple murder. But there is a witness who managed to escape and that could incriminate him. Santos undertakes an investigation to locate and eliminate the witness. Meanwhile, Chacón a judge in charge of investigating the triple murder, meticulously advances in the search for the murderer. Santos and Chacon soon discover that what seemed a simple case of drug trafficking is actually something far more dangerous.

Barbara is a fanciful drag queen who steals a valuable briefcase and runs to the plains. He crosses path with Sixto, a young farmer escaping from a drug lord. They join in a dangerous journey through harsh lands and their relationship grows from conflict and mistrust into an particular friendship.

In a time uncertainty times, Luisa and Juan Bautista feed their love, but the war separates them and she ends in prison. They must struggle to be together again and stay true to their love and ideals.