Barr Messenger escapes to Mexico after a frame-up. He is in love with Betty Brownlee, who disappears after $10,000 is stolen from the firm she works for. It is thought she took the money. In Mexico, In Mexico, Barr finds Betty working in a saloon for "Red" McGee, the chief henchman of "Bull" Keeler's (the Kingfish) Kingfisher gang.

The Trail of the Hound is a 1920 silent Western.