The existence of mankind hangs in the balance as two warring factions of aliens do battle in Mark of the Astro Zombies. The film begins with an invasion of Earth by aliens who plan to turn human beings into zombies. They gather high-level government officials and attempt to get from them certain knowledge and information they will need. A kind race of aliens lands on Earth and decides to try and stop the evil ones from succeeding with their plans.

When two athletic girls are forced to become drug mules and are then murdered by the mob, their girlfriends from the gym unite to avenge their deaths.

Beautiful women join a coven and sell their souls to Satan for fame and riches.

A 7 foot tall skeletal samurai warrior returns from the grave and picks up where he left off centuries ago, murdering folks and collecting brains.