Native American business partners, Marty and Jess, embark on a journey to the American Southwest to shoot a film. The fun lasts until Jess vanishes without a trace leaving a worried Marty to deal with her past, false allegations and racism while trying to find her friend.

Mexican aviation exec Renato is shocked to learn that he has an American half-brother he never knew about: free-spirited Asher. They are forced on a road trip together, tracing the path their father took from Mexico to the U.S.