An old film director, unhappy with the movie he's shooting about a Hungarian circus stranded in Rome during the 1956 anti-Soviet uprising, faces divorce from his producer wife and other problems.

Robert McCall finds himself at home in Southern Italy but he discovers his friends are under the control of local crime bosses. As events turn deadly, McCall knows what he has to do: become his friends' protector by taking on the mafia.

After the unexpected death of the Pope, Cardinal Lawrence is tasked with managing the covert and ancient ritual of electing a new one. Sequestered in the Vatican with the Catholic Church’s most powerful leaders until the process is complete, Lawrence finds himself at the center of a conspiracy that could lead to its downfall.

Stranded in rural Italy without transportation or language skills, an American couple on the verge of adopting tries to reconnect during a disastrous vacation, as their fears and relationship problems threaten to boil over.

While racing up Italy's wild coast to reclaim his stolen work, queer Renaissance painter Caravaggio realizes that leaving his beautiful lover behind, to chase glory in Rome, was a betrayal that will cost him his life. As his final moments unfurl like a fever dream, he glimpses at the angel who has been guarding him all along - and understands that even in death, his art will burn on.