Daisato, a second-rate, third-generation superhero, annoys his neighbors with the noise and destruction he causes on the job. But a heroic public image is the least of his concerns. Besides defending Japan from bizarre monsters, he must deal with an agent seeking to brand him with ads, a superhero grandfather with Alzheimer's and a family embarrassed by his incompetence.

A novice red blood cell and a relentless white blood cell work together to protect their human from invading germs, pathogens and other threats.