Young Cabiria is kidnapped by pirates and sold as a slave in Carthage. Just as she's to be sacrificed to Moloch, Cabiria is rescued by Fulvius Axilla, a good-hearted Roman spy, and his powerful slave, Maciste. The trio are broken up as Cabiria is entrusted to a woman of noble birth. With Cabiria's fate unknown, Maciste punished for his heroism, and Fulvius sent away to fight for Rome, is there any hope of our heroes reuniting?

Pompeii 79AD, mere days before the Vesuvian eruption. Glaucus and Jone are in love with each other. Arbaces, the Egyptian High Priest, is determined to conquer Jone. Glaucus purchases Nydia, the blind and long-suffering slave. Nydia falls in love with Glaucus and asks Arbaces for his help. He gives her a potion to make Glaucus fall in love with her-- In fact, a poison which will cause violent insanity.

Scientist Galileo Galilei was engaged in his studies, but a servant of his attempts to seduce his daughter, and denounces Galilei to the Holy Office.