Life seems perfect for John Brennan until his wife, Lara, is arrested for a murder she says she didn’t commit. Three years into her sentence, John is struggling to hold his family together, raising their son and teaching at college while he pursues every means available to prove her innocence. With the rejection of their final appeal, Lara becomes suicidal and John decides there is only one possible, bearable solution: to break his wife out of prison.

After one short blind date, Mary Horowitz, a brilliant and eccentric crossword constructor, is convinced that Steve, a CCN cameraman, is her soul mate. Because his job takes him hither and yon, she crisscrosses the country following Steve, with the encouragement of a reporter, turning up at media events he's at to convince him they are perfect for each other. Along the way, she befriends an assortment of misfits who accept her for who she is, leading her to reassess her reasons for this strange journey.

On a flight from Los Angeles to New York, Oliver and Emily make a connection, only to decide that they are poorly suited to be together. Over the next seven years, however, they are reunited time and time again, they go from being acquaintances to close friends to... lovers?

An uptight, conservative businesswoman accompanies her boyfriend to his eccentric and outgoing family's annual Christmas celebration and finds that she's a fish out of water in their free-spirited way of life.

Special Agent Jennifer Marsh works in an elite division of the FBI dedicated to fighting cybercrime. She thinks she has seen it all, until a particularly sadistic criminal arises on the Internet. This tech-savvy killer posts live feeds of his crimes on his website; the more hits the site gets, the faster the victim dies. Marsh and her team must find the elusive killer before time runs out.