When an attack on the O.W.C.A. incapacitates the animal agents, only Agent P and his animal trainees can save the day. Carl and Monogram fend for themselves.

Doofenshmirtz's latest "-inator" accidentally turns the citizens of Danville into contagious mindless repulsive pharmacists that look like him who run rampant all over town. Agent P and the kids must work together to save Danville and avoid becoming mindless repulsive pharmacists themselves.

Phineas and Ferb team up with the Avengers to save the world from Dr. Doofenshmirtz and a group of dangerous supervillains.

Phineas and Ferb turn the city of Danville into a giant thank you card for Santa Claus because they feel nobody ever thanks him for all the joy he brings to the world. Doofenshmirtz uses a device called the "Naughty-inator" to put the city of Danville on Santa's naughty list.

Phineas and Ferb get trapped in an alternate dimension where the evil Doofenshmirtz rules the tri-state area. They must find a way back home with the help of their pet platypus named Perry, who they discover is a secret agent.

Phineas and Ferb travel across the galaxy to rescue their older sister Candace, who has been abducted by aliens and taken to a utopia in a far-off planet, free of her pesky little brothers.

It's the summer solstice, so Phineas, Ferb, and their friends decide to travel around the world in one day in an effort to create the "biggest, longest, funnest summer day of all time". But not everyone believes they can actually achieve what they have set out to do, especially Buford. Candace tags along because Jeremy is on a trip to Paris, and she fears that there he may meet other girls. Also, Isabella finds her affections for Phineas sorely tested when his steadfast focus on achieving his goal puts pressure on her. Meanwhile, Dr. Doofenshmirtz takes a father trip to Tokyo, Japan with Vanessa, but sets out with Perry and Major Monogram to find her when she joins Phineas, Ferb and the others.

When L.O.V.E.M.U.F.F.I.N. moves the Earth further from the sun, Phineas and Ferb must find a way to save summer and prevent a new ice age.