Saint Street is a classic American Christmas tale for the entire family. The story follows Percy who is a good man, but has found himself caught up in the riches of the world and is neglecting his most prized possession – his family. Christmas Eve has arrived and Percy is still hard at work late into the night, once again breaking his promises to his wife and kids that he would leave early so that they could drive to their traditional family Christmas party. After being warned time and again to change his ways from a heavenly being from beyond, Percy is about to experience some grave consequences for his actions. In a series of tragic events, Percy faces humble circumstances after losing everything in a car accident – his family, job and home. Paralyzed from the waist down and confined to a wheelchair, he is forced to be homeless and live in the gritty world of misfits on Saint Street.

When inept, self-proclaimed survival experts Kaduche and Wynn discover the world's impending destruction, they pull their act off YouTube and enter Epic Mode to save the Earth. Teaming up with their nemesis, the girl of their dreams, and an eccentric visionary known as the Oracle, the group sets out to battle domestic terrorists, disenfranchised Russian communists and brain-eating zombies.