The Dematerialization Phenomenon, in which the real world becomes digital, has become a problem and must be resolved immediately. After hearing of this incident, Netto and Rockman left off after their father and Network Researcher, Yuuichirou. He also had found news of an invasion in the computer of the Trinity Brain trust company: 'The Earth itself will understand the way things stand in the cyber world'. In order to destroy the program causing the incident, Netto and Rockman have to go deep underground. But old enemies await them there, as well as new ones. As they fought each other, the vicious cyber-life, Nebula Grey, awakens. The Dematerialization Phenomenon will not be stopped unless Nebula Grey is defeated.

Nobita travels to the future to show his beloved grandma his bride, but adult Nobita has fled his own wedding.

Goro briefly returns to Japan after a triumphant campaign in the US. He is heading towards Fukuoka where he played baseball when he was a fifth grader. Having just moved into a new town, this is where Goro faced a critical point in his life.