Tepito is a neighborhood of Mexico City, where the dreams of many destitute people become real. But Tepito is also run by organized crime and corrupt politicians, impunity reigns and justice is non- existent. Here will take place the story of two foolishly proud young men, who were once best childhood friends, and now are blinded by greed and turn against each other. Their intentions are to destroy their families and eventually their own lives.

Oscar is a handsome boy who, in a night out with his friend, meets Bárbara, a Venezuelan girl with whom he falls in love. He does not imagine that Elvis, Barbara's ex-boyfriend, will come to collect a debt that he had pending with her.

Brenda and Sara manage to escape from prison and return to the neighborhood to start a business and, with the help of El Sapo, open another elite whorehouse, which protects a very powerful person.

Silvana becomes embroiled in a love triangle with two drug bosses.

Paulina is a stripper, who falls in love with Adrián hoping to forget Antonio, the love of her life. She does not expect that by being with Adrián she will receive the best news in her life, and her destiny puts a third man on her way, without expecting that in a short time she will fall in love with the person least indicated for her.

In the rearrangement of the territories, the mafia puts all its cards into play, several capos have been released and revenge is activated, beautiful women are put into action, so that using their best weapons, they bring order among these capos.

Brenda sets up a white slave business after escaping from prison. Not a woman who has entered her business comes out alive.

After being the best hit man of all time, now he has to be the victim of a revenge that not even with all the men in the world could finish him off. However, they only left him with a thirst for revenge which increased his level of cruelty to settle scores, because if anyone knows about this perverse business, it is the famous Quebrantahuesos.

After their father's death, two brothers dispute their father's inheritance and unintentionally the same woman.