An anthology film and friendship tale that takes place in St. Louis in the late 1980s during the height of the AIDS crisis. The story follows a man who has just found out one of his friends is HIV positive — a death sentence that, back then, usually meant the person had about twelve months to live. The main character goes on a game show in order to raise money for a car to drive his friend to Mexico where he can receive a popular, but later proven ineffective, treatment for the virus.

Ella (Jackie Manker) returns to her mom's summer cottage in Centralia, Illinois and connects with a younger jazz musician Tyler (Cody Heuer) at her stepfather's wake. On a date, she runs into an ex-boyfriend (played by baseball great Adam Wainwright). To round out the love triangle, her mother Naomi (Sandy Sparks) has another man in mind -- age-appropriate Dr. Gordon (Bill Finkbiner).