In August 1969, Charles Manson's followers killed seven people on his orders. Why? Explore a conspiracy of mind control, CIA experiments, and murder.

CIA Drugs R Us is a comic sequel to the film, Drugs as Weapons Against Us: The CIA War on Musicians and Activists. The film continues focusing on U.S. intelligence's use of drugs in the murderous targeting of activists. It particularly covers John Lennon, Kurt Cobain, and Tupac Shakur. The film further details the CIA's Project MK-Ultra involvement with The Manson Family regarding activist actors and The Black Panthers. It also details examples regarding U.S. intelligence, drugs and the antiwar Students for a Democratic Society (SDS). The film then discusses the CIA's MK-Ultra front group, The Human Ecology Fund, continuation, along with Maryland's Catholic Church sex abuse scandal featured in the Emmy-nominated documentary series, The Keepers.