A pair of not-too-bright Mexican cats, one shorter-tempered than the other, decide to chase Speedy Gonzales, the fastest mouse in all Mexico.

In a Mexican restaurant, a man named Jose tells to his friend, Manuel, the story of Senorella, a Mexican version of Cinderella. Senorella's dream of liberation from her slavish existence under the yoke of her wicked "Strap-mother" and "Strap-seesters", comes true after her fairy godmother grants her a night as a ravishing beauty at the fiesta at a bullfighter's father's estate.

Speedy Gonzales' lethargic cousin, Slowpoke Rodriguez, comes to visit Speedy's hacienda, to the delight of Sylvester Cat, who is confident he will be able to catch Slowpoke for dinner.

Sylvester Cat is a guard at a Mexican experimental laboratory where mice are confined for research. The families of the captured mice place a call to Speedy Gonzales, the fastest mouse in Mexico, to help them rescue their compadres. Speedy comes and engages in the usual battle of wits and feet with Sylvester.

Poncho and Toro turn their hunger pangs toward a certain grasshopper with attitude who sounds just like John Wayne!

When Pancho and Toro caught the El Kukaracha, they thought they would share it for breakfast tomorrow, but when they're asleep, one of them would sneak to the breakfast and eat it themselves.

A clumsy bird named Crazylegs Crane is chasing Toro and Pancho for a meal. When the two frogs arrive to the room full of bottles containing nitroglycerine in the small house, the two frogs thought they could trick the bird by pretending to drink it by filling empty nitroglycerine bottle with water, but Pancho accidentally switched the bottle with real nitroglycerine, and the bird saw Toro drinking it and bird didn't want him to blow up, and let the the toads do what ever they want. The bird took frogs to Havanna, and bird went to Las Vegas after frogs arrived at Havanna. Two frogs happily danced, and blew up! The frogs, instead, arrived at Heaven!

Proud parents Poncho and Toro "adopt" Crazylegs Crane when they "find" his egg.

Pancho and El Toro's lake has completely dried up, so they decide to take refuge in a nearby neighbor's swimming pool. They just have to get past the giant dog first...

Crazylegs Crane gets an amnesia and Toro and Pancho tricks him into thinking he's a frog. They use him to guard them from the Blue Racer, the fastest snake in the west, who wants to have them for a meal.