In the 1840s, Ramsey MacKay, the driver for the struggling Wells Fargo mail and freight company, will secure an important contract if he delivers fresh oysters to Buffalo from New York City. When he rescues Justine Pryor and her mother, who are stranded in a broken wagon on his route, he doesn't let them slow him down and gives the ladies an exhilirating ride into Buffalo. He arrives in time to obtain the contract and is then sent by company president Henry Wells to St. Louis to establish a branch office.

One of the last bills signed by President Lincoln authorizes pushing the Union Pacific Railroad across the wilderness to California. But financial opportunist Asa Barrows hopes to profit from obstructing it. Chief troubleshooter Jeff Butler has his hands full fighting Barrows' agent, gambler Sid Campeau; Campeau's partner Dick Allen is Jeff's war buddy and rival suitor for engineer's daughter Molly Monahan. Who will survive the effort to push the railroad through at any cost?

Kathleen O'Moore returns to her home in rural Ireland and becomes torn between the affections of Michael Rooney, a poor but honest man, and the wealthy squire with the power to make her dreams come true.

Binkie Stuart, a child star whose career briefly flourished before the outbreak of war in 1939, takes the titular role in this heart-warming musical charting the adventures of a little orphan girl in the difficult days of pre-war Ireland. Starring alongside Hollywood siren Maureen O Hara in an early role, Britain's answer to Shirley Temple plays a spirited young girl left in the clutches of a cruel guardian aunt.

Bruce Edwards returns to his hometown to take possession of his late father's estate, but Sam Willetts presents him with documentation proving that Mr. Edwards traded the estate for worthless swampland. Bruce takes a job in the village tavern and romances June Gordon, whose mother suspects Willetts of foul play. When Willets falsely accuses Bruce of theft, the young man escapes. Bruce later regains his father's estate by convincing Willets that the swampland is valuable for manufacturing purposes. Afterward, June and Bruce leave on their honeymoon.

After Mary Carroll's husband learns that she has had an affair, he challenges her former lover to a duel and is killed. Mary is thrown out by her husband's wealthy family and separated from her little boy, John Carroll, Jr. Years later, John Jr. falls in love with Ruth Fulton, the daughter of the horse trainer for Rex Burleigh. When her father dies, Ruth accepts Rex's offer to care for her, but she leaves the expensive apartment he has provided when she learns his true motives.