On March 15, 2007, Eric Clapton's world tour stopped at San Diego's iPayOne Center (originally the San Diego Sports Arena and now the Valley View Casino Center). The band lineup for the tour continues to be a firm fan-favorite, with Derek Trucks and Doyle Bramhall II on guitars, Chris Stainton and Tim Carmon on keyboards, Willie Weeks on bass, Steve Jordan on drums and backing vocalists Michelle John and Sharon White During the set, EC's long-time musical inspiration, JJ Cale, sat in for five songs, including three from their Grammy-Award winning album, The Road To Escondido, released in 2006.

In Concert: A Benefit for the Crossroads Centre at Antigua is a live concert film featuring performances by the British rock musician Eric Clapton and invited friends, such as David Sanborn, Sheryl Crow, Mary J. Blige and Bob Dylan.[citation needed] The DVD and VHS releases hit the market on 26 October 1999 under license of Warner Bros. Records. The concert tickets revenue was donated to the Crossroads Centre Foundation. It was the first Crossroads Guitar Festival, although titled differently at the time.[1] The release reached various national charts and sold more than 225,000 copies worldwide.

Eric Clapton, one of the world’s pre-eminent blues/rock guitarists, once again summoned an all-star team of six-string heroes for his seventh Crossroads Guitar Festival in 2023. Held at the Crypto.com Arena in Los Angeles, California, the two-day concert event raised funds for the Crossroads Centre in Antigua, the chemical dependency treatment and education facility that Clapton founded in 1998. With actor Bill Murray as the Master of Ceremonies, the 2023 festival featured outstanding performances by Clapton, Joe Bonamassa, Gary Clark Jr., Sheryl Crow, Eric Gales, H.E.R., Christone “Kingfish” Ingram, Los Lobos, John Mayer, The Marcus King Band, Roger McGuinn, John McLaughlin, Santana, The Wallflowers, and many more.

To Save a Child: An Intimate Live Concert is a live album by British rock musician Eric Clapton, released on 26 April 2024. The album features a concert by Clapton that was recorded in London in front of a small audience on 8 December 2023, which featured a guest appearance by Dhani Harrison on the song "Give Me Love (Give Me Peace on Earth)", a cover of George Harrison's 1973 song. Proceeds from the sales of To Save a Child: An Intimate Live Concert were donated to aid children in Gaza in response to the Israeli invasion of the Gaza Strip.

Double-DVD Captures Highlights from Festival With Performances and Collaborations by Guitar Wizards Eric Clapton, B.B. King, Buddy Guy, Jeff Beck, John Mayer, Robert Cray, Robbie Robertson, Sheryl Crow, Derek Trucks and More

10-time Grammy Award-winning singer/songwriter/producer Kenneth Babyface Edmonds delivers an intimate set for MTV Unplugged, featuring performances of I'll Make Love To You and Whip Appeal plus guest duets with Eric Clapton and Stevie Wonder.