Thai drama tells the story of a mother who sends both her daughters to study in Bangkok, hoping that they can get good jobs to raise money for the family. Their determination and relationship is put to the test when the younger sister gets too intimate with the man they are living with.

Based on a true story, Sam Chuk exposes 7 teenagers in a neighborhood called Sam Chuk, whose lives are entangled with troubles and devastated by using drugs. Their local teacher is seriously concerned the drugs problem and begins to cope with them by giving them a chance to prove themselves.