Dr. Jack Hammond has best chances to become medical superintendent in the clinic. So he's completely absorbed in his work and has no understanding for his teenage son Chris' problems with school. By accident one of them drinks a brain-exchanging serum, and it switches their identities. This leads of course to extraordinary complications in school and at work, but also to insight in the problems and feelings of each other.

Mitchell Osgood dreams of being a famous writer, but the book he has written constantly is rejected by the editors. When the psychopathic killer Albert Merrik is released from prison after 15 years, Osgood believes that writing down the history of his crimes could be his breakthrough. Although he refuses to talk to him at first, Osgood follows him around and offers him a job in his book shop. To get the right impressions for his book, he feels that he has to experience Merrik psychopathic again.

A woman is torn between her boyfriend's ending their relationship and being separated from his young son with whom she has bonded.