Following World War III, four survivors at a desert military installation attempt to drive across the desolate wasteland of America to Albany, where they hope more survivors are living, using a specially built vehicles to protect themselves against the freakish weather, mutated plant and animal life, and other dangers encountered along the way.

An accidental overdose of gamma radiation causes a mutation in scientist David Banner's DNA: now whenever he becomes angry, he metamorphoses into a seven-foot-tall, 330-pound, mindless muscular green creature.

Norma Jean Baker finds her way to Hollywood and is turned into sex symbol Marilyn Monroe.