Danny Mitchell and his canine pal Rusty befriend blind girl Penny Moffatt. Feeling cheated by life, Penny resists all efforts to cope with her handicap. But with Rusty's help, the girl gains a new lease on life and agrees to adopt a seeing-eye dog.

Sherlock Holmes investigates a series of so-called "pajama suicides". He knows the female villain behind them is as cunning as Moriarty and as venomous as a spider.

Dagwood enters the Army Reserve and Blondie visits only to discover that he has caused all sorts of problems which lead to numerous conflicts.

An escaped convict, injured during a robbery, falls in love with the woman who nurses him back to health, but their relationship seems doomed from the beginning.

When Pa wins a jingle-writing contest, he and Ma head for New York City. They they get in trouble with gangsters when they lose some stolen money which they had already agreed to deliver to one of the thugs.

A missionary tries to outwit the U.S. government and smuggle Chinese orphans into the country.

An Episcopal Bishop, Henry Brougham, has been working for months on the plans for an elaborate new cathedral which he hopes will be paid for primarily by a wealthy, stubborn widow. He is losing sight of his family and of why he became a churchman in the first place. Enter Dudley, an angel sent to help him. Dudley does help everyone he meets, but not necessarily in the way they would have preferred. With the exception of Henry, everyone loves him, but Henry begins to believe that Dudley is there to replace him, both at work and in his family's affections, as Christmas approaches.

An orphan helps a doctor fight an epidemic in a small western town, in one of Allan Dwan’s closely observed studies in Americana.

Living with his family in Baltimore, 9-year-old Lewie Penrose claims that he can converse with horses--and also pick the winners of upcoming races. When it appears as though Lewie is telling the truth, he attracts the interest of gambler Rich Roeder who needs a "sure thing" in the upcoming Preakness. Meanwhile, Lewie's older brother John carries on a romance with the lovely Martha.

The boys are working at the local boxing arena where their friend, Jimmy Higgins, is boxing. During a crooked match Jimmy is killed. The boys seek out his older brother, Johnny, a former boxer who gave up the sport rather than go crooked, and help train him to get back in the ring. They try to get him a shot at the title, and when they do the same crooked gangsters that were behind Jimmy's death try to get Johnny to take a dive.