Andrea, a successful veterinarian who loves her job and is in a relationship with Lucio, an up-and-coming lawyer who grew up in the country. Lucio has some news for Andrea: his mother is turning 60 and is throwing a big party to celebrate. Andrea visits the town where Lucio was raised for the first time and would like to become very close to his family, especially her new Mother-in-law Blanca, who is an overprotective mother, ultra-conservative and always thinks she’s right about everything. Andrea tries to fit in by tolerating all her quirks and harsh treatment during the torturous weekend.

Dante travels to Lagos de Moreno to see an old girlfriend who is about to marry. By chance he meets an Italian tourist named Domenica and they spend the night wandering through the city streets. Among memories of lost loves, Dante and Domenica eventually discover they are soul mates.

During the last moments of a romantic involvement with an older man, Martina finds herself deeply overwhelmed by disappointment and confusion, left alone to question who she really is.

At the Holly Day of The Deaths, a mother returns and finds that her three sons are desconsidered, ugly and lazy.

Hostage negotiator Alan Bender is called to rescue the president from a kidnapping, only to find himself also mediating to save his wife and marriage.

After hearing the news of an asteroid just days away from impacting Earth, Paola enters into a deep conflict as she evaluates what she has done with her life up to that point and how she hopes to face her last days, just as Santiago, a former lover, reappears, seeking to close their unfinished story.

In a cozy bistro, an increasingly heated discussion between two good buddies reveals their latent sexual prejudices, as one admits to feeling finally set free by a book he has just read.

A punk band decides to hire a keyboard player in order to change their sound, despite the fact that this talented musician has Down Syndrome.

Minerva, a single mother, works long hours a day to keep her ailing daughter in the hospital. One day, a mysterious man arrives at her door offering her to work in the translation of an ancient book in exchange for a substantial sum of money. Minerva accepts without knowing that this will change her life and that of those around her forever.

Two longtime friends decide to attempt the Guadalupe Reyes challenge, which consist of drinking everyday from December the 12th (Day of Our Lady of Guadalupe) until January the 6th (Epiphany Day, the Feast of The Three Kings).