The tranquility of Uncle No Rules's home is disturbed when a mysterious variety-show equipped with a studio audience and charismatic host (Marky Ramone) descends upon the household.

Evil voodoo-practicing serial killer Shadow gets executed for murdering pregnant women. Twenty years later the prison Shadow was put to death at has been turned into an experimental women's penitentiary. Tough and fiercely autonomous new inmate Solitaire has some kind of link with Shadow. When Shadow and his lethal shambling zombie minions are resurrected, it's up to Solitaire to stop them.