The Stooges are key witnesses at a murder trial. Their friend Gail Tempest, who dances at the Black Bottom cafe where the Stooges are musicians, is accused of killing Kirk Robin.

Dr. Paul Carruthers is frustrated because he thinks his employers, Mary Heath and Henry Morton, have cheated him out of the company's profits. He decides to get revenge by altering bats to grow twice their normal size and training them to attack when they smell a perfume of his own making. He mixes the perfume into a lotion, which he offers as a gift to Mary and Henry. When they turn up dead, a newspaper reporter decides to investigate.

While vacationing without her busy British diplomat husband, a married woman falls for another man.

Set in a western town, the stooges are working as waiters in a saloon with the three girls they hope to marry. The proprietor of the saloon is a crook who, with his partner, has buried $40,000 of stolen money. The boys go prospecting in hopes of raising enough money to pay off the debts of their fiancée father, who owes money to their boss. They dig up the stolen money, which the crooks recognize as their loot and abscond with. A wild chase ensues, ending with the bad guy's car crashing into the Sheriff's office.

Roscoe believes he is in line to receive a large inheritance, but the reality is considerably more psychopathic-- no, nuts.

A disruptive Annapolis naval cadet refuses to tow the line and so gets booted out of the prestigious academy. Later, he takes to designing speedboats. They are innovative and soon the Navy comes a-knocking in hopes that he will design a fast and easily maneuverable boat to carry torpedoes.

The stooges are actors traveling to perform at a fiesta in Mexico. After they accidentally switch suitcases with that of Dolores, a lovely senorita they met on trip down, they must sneak into her house to retrieve their suitcase. When they are confronted by her jealous husband he vows to kill them if he sees them again. At the fiesta where they are performing a comedy bullfight (Curly is the matador, Moe and Larry are in a bull costume) the husband bribes the attendants to let a real bull into the ring. Curly knocks the bull out with a head butt and becomes a hero.

Judy Walker is a poor songwriter who, through mistaken identity, gets her songs played on the radio.

In the early 1900s, as the Panama Canal is being built, a group of doctors try to discover a cure for yellow fever, a disease that is decimating the workers constructing the canal.

After graduating college an aspiring photographer lands his first job--with a big city newspaper.