Larry Flynt is the hedonistically obnoxious, but indomitable, publisher of Hustler magazine. The film recounts his struggle to make an honest living publishing his girlie magazine and how it changes into a battle to protect the freedom of speech for all people.

In 1590, the Diet of Augsburg ruled that gypsies were the spawn of Satan and, therefore, had no rights whatsoever. The ruling allowed Christians to kill gypsies without penalty, which sparked the church to organize a small group of religious assassins to carry out the dirty work. Unfortunately, the band of killer priests were not informed that the gypsies had made a pact of protection with a powerful werewolf clan, so all hell broke loose. Four hundred years later, the bloody war between the church, gypsies and werewolves rages on and it's up to a small-town police chief to end it or die trying.