In 1987, a disillusioned door to door orange salesman horrifically murders his first victim. Move forward 27 years and a land developer is buying an orange grove. He and his 3 friends plan a fishing trip to get his head around the pending transaction, unbeknownst to them, his estranged wife and her new boyfriend have also chosen the very same location for a break. The usual strange noises and unnerving situations ensue when they congregate at a secluded cabin, as The Orange Man eliminates them 1 by 1 with the aid of his prosthetic hook and a bag of oranges!

Lonely delivery man Joseph falls in love with an alcoholic prostitute named Karen, who frequents one of the stops along his route. Though they soon become friends, Joseph is unable to figure out what makes the very-guarded Karen tick. While Karen drowns the sorrows of her mysterious past, keeping him at bay, Joseph remains committed to winning her affection, resorting to extreme measures in his search for the key to her heart. Embarking on a dark journey with a mystical relic -a 'hand of glory,' whose legend purports the ability to unlock any door- Joseph soon discovers that such feats come at a dire price.