At the beginning of the 20th century, a junior resident takes an interest in a newly-arrived patient, a young Italian woman who has mysteriously developed schizophrenia. To identify the causes of her condition, he employs psychoanalytic methods to dig into her sexual past, despite objections by the old-fashioned chief physician.

Borderline is about a woman, victim of the cruelty and violence, and a man, Gabriel, a fifty-year-old director in search of celebrity.