Dagwood inadvertently gets cornered in to resigning. When his wife Blondie tries to ask Dagwoods boss Mr. Dithers for his job back, he ends up hiring her instead. This doesn't sit too well with Dagwood. Blondie's sister comes to visit, and Dagwood is put in a compromising situation with another woman.

Cookie is born, producing unmitigated joy in the Bumstead household. Adding to the chaos a new baby always creates is the appearance of Hans Conried as a cynical author who becomes caught up in the Bumstead lifestyle.

Mr. Dithers is trying to encourage a businessman to build a war-time manufacturing plant on land he owns while Dagwood tries to prevent the businessman from learning his daughter is involved in a local theatre production.

Dr. Leon Kravaal develops a potential cure for cancer, which involves freezing the patient. But an experiment goes awry when authorities believe Kravaal has killed a patient. Kravaal freezes the officials, along with himself. Years later, they are discovered and revived in hopes that Kravaal can indeed complete his cure. But human greed and weakness compound to disrupt the project.

In this newspaper drama, a female reporter and a newsreel cameraman are both assigned to cover the Sino-Japanese war. They meet on the boat ride over and decide to team up. They are further assisted by a Chinese cameraman. The three of them manage to expose of spy ring operating out of the Shanghai office of the woman's newspaper.

A kindly, enthusiastic, newly-arrived American immigrant from Hungary is forced to turn to a life of crime after his face is badly disfigured in a hotel fire.

A gangster takes a doctor and his family hostage.

Joan Daley, a New York booking/press agent, attempts to recruit two local stand-ins, Jinx Terry and Lois Morgan, when the Cuban sister-act, Marianela and Rosita she as booked into the nightclub for which she works fails to materialize. Complications arrive when the real Cuban sisters show up.

While attending stenographer school, Tillie Jones meets office boy Mac, who falls in love with her at first sight. Though Tillie likes Mac as a friend, she continually throws him over for handsomer men.

El and his new bride go on their honeymoon; no matter where they go, they keep running into her former husbands.