After a comet disrupts the rain cycle of Earth, the planet has become a desolate, barren desert by the year 2033. With resources scarce, Kesslee, head of the powerful and evil Water & Power Corporation, the de facto government, has taken control of the water supply. Unwilling to cower under Kesslee's tyrannical rule, a pair of outlaws known as Tank Girl and Jet Girl rise up, joining the mysterious rebel Rippers to destroy the corrupt system.

A mysterious woman comes to compete in a quick-draw elimination tournament, in a town taken over by a notorious gunman.

Seven junior-high-school girls organize a daycare camp for children while at the same time experiencing classic adolescent growing pains.