Five college women buy the old Hokstedter place for their new sorority house. They got it cheap because of the bloody incidents from five years before. They decide to stay in it for the night so they can meet the movers in the morning, but begin to get the creeps when the weird neighbor Orville Ketchum starts poking around. Shortly after the women take showers and consult a Ouija board they begin experiencing an attrition problem.

Five of Hollywood's leading scream queens get together in a creepy mansion and decide to get in the hot tub (as true scream queens would). They talk in the tub and exchange secrets on the do's and don'ts of being a scream queen.