Lizzie, a high-end event planner, lies awake nightly while her devoted fiancé Josh rests peacefully. When a sleep-deprived incident causes her to run into Billy, a low-key bartender who is just as sleepless and frustrated as she is, they discover that they can only fall asleep while next to each other.

Everyone has "that" friend - the one who shows up uninvited, drinks all your booze, and hits on your girlfriend - who we all secretly hate and wish would just go away; one night, a group of friends decide enough is enough and there's only one way to get rid of him for good - they MUST KILL KARL.