Goonjan, a young woman working in an advertising agency in Kolkata, is about to marry her office colleague Siddhartho. Elsewhere in the same city Arjun is suffering from cancer. His bimbette tenant, Amrita, daughter of Shubhendu, is a nurse at a private hospital near the Eastern Metropolitan Bypass. Apart from her daily chores, Amrita decides to take care of Arjun. Meanwhile, as the wedding invitations begin, Goonjan comes to know about the first crush of her life, Arjun. On the day of meeting Arjun, when Siddhartho goes to leave Goonjan there, he meets his unrequited love Amrita. Will the magic of a new love story develop in the heart of the City of Joy? Will the college crush remain just a long lost crush, or will it develop into a story of love at least for once? On the other hand, will Siddhartho try to get Amrita back, or will he spend the rest of his life with his current love, Goonjan? Fate has its ways.

Kadambari Aajo explores the life of a married woman, Kadambari, who forms a unique connection with an English professor during a film shoot in North Bengal and that's where the interesting part of the story begins.