In the Pacific Northwest of 1993, the sky is black, the night is wet, and the Grunge Monster stalks a college campus. To survive, an attractive group of students who know the anthropological secret of a body's 213 bones must uncover the history of the worst campus killer since Ted Bundy.

Dr. Lily Houghton enlists the aid of wisecracking skipper Frank Wolff to take her down the Amazon in his dilapidated boat. Together, they search for an ancient tree that holds the power to heal – a discovery that will change the future of medicine.