Invicta FC 5: Penne vs. Waterson was a mixed martial arts event held on April 5, 2013. Shannon Knapp announced during Invicta FC 4 that the event will be headlined by a co-main event of Jessica Penne defending her Invicta FC Atomweight Championship against "The Karate Hottie" Michelle Waterson along with a flyweight championship bout between Vanessa Porto and Barb Honchak and that Sarah Kaufman would make her Invicta debut on the show. The show was originally targeted for April 13, however Knapp announced they would change it to April 5 after the UFC announced a show on that date.

Invicta FC 18: Grasso vs. Esquibel was a mixed martial arts event headlined by a strawweight fight between undefeated Alexa Grasso and Jodie Esquibel. The winner of the main event is expected to receive the next strawweight title shot against champion Angela Hill. The original co-main event was to be Irene Aldana facing undefeated Brazilian fighter Taila Santos to determine who challenges Tonya Evinger next for the bantamweight championship, however VISA issues forced Santos off the card and the fight was removed. Lynn Alvarez was scheduled to fight undefeated Indian fighter Manjit Kolekar but VISA issues forced Kolekar off the card and she was replaced by Mizuki Inoue. Agnieszka Niedzwiedz was scheduled to fight Claudia Rey but Rey was also unable to make the event due to VISA issues and was replaced by Christine Stanley. Aldana, Rey, and Santos are now being scheduled for the next event.

Invicta FC 20: Evinger vs. Kunitsakaya was a mixed martial arts event that was headlined by Invicta FC bantamweight champion Tonya Evinger defending her title against Russian newcomer Yana Kunitsakaya. In the co-main event, strawweight champion Angela Hill defended against Kaline Medeiros.