Cuba Libre focuses on the return of Cuban transgender actress Phedra de Cordoba, from the Satyros theater group, to Havana after 53 years away from her country. The film discusses the struggle for gay rights in an extremely macho environment such as the island ruled for decades by Fidel Castro, now led by his brother Raul.

Jorge, bastard child of the infamous Red Light Bandit, decides himself to pursuit a life of crime after meeting with his father, who has been incarcerated for the last 30 years.