Rance Roden plans to kill off all the buffalo and thus cause the Indians to riot. After they destroy the US Cavalry, Rance and his gang will take over the West. Meanwhile, a Boston magazine gets wind of the buffalo slaughter and sends editor Kenneth Cabot and his associates to Casper, Wyoming to investigate.

Professor Brookfield along with daughters Peggy and Susan move to small town Pasadena, California. Their new neighbor Mrs. Fielding helps them move in, and urges the girls to participate in the annual Rose Bowl beauty pageant. Meanwhile Mrs. Fielding's son Tom makes eyes at Peggy but she's smitten with a famous football star so she tries to redirect his interest to Susan.

Murder occurs when several of the most popular radio personalities of the '40s converge on a desert resort.

Young auto mechanic Dan Brady takes $20 from a cash register at work to go on a date with blonde femme fatale Vera Novak. Brady intends to put the money back before it is missed, but the garage's bookkeeper shows up earlier than scheduled. As Brady scrambles to cover evidence of his petty theft, he fast finds himself drawn into an ever worsening "quicksand" of crime.

Joyce Harper is an ex-Army nurse who enters police work with the L.A. Police Department, when her friend Ruby gets involved with a petty crook, Max Taylor refuses to listen to Joyce's warnings, and eventually marries the hoodlum. Joyce gets through the detailed trained required to become an L.A. policewoman, and she and her newly-assigned detective partner, Harvey Gates cleanup up a skid-row Bar-girl scheme.And she and Gates are told to get the goods on a narcotics gang ran by Richard Cott , and Ruby and Max Taylor reappear.

A homicide detective suspects a playwright who bases his play on a murder.

Maggie is resentful of being pointed out and laughed at in public because she resembles the cartoon character in the George McManus comic strip "Bringing Up Father." She visits McManus in his studio office and tries to persuade him to stop drawing the syndicated comic-strip. He tells her he will...in 1959. Maggie, not getting any younger, retains counsel and takes McManus to court.

Comedy and music in the night court.

In a mock fraternity initiation, a group of Yale students haze Paul Browning for tattling. When he learns that the leader of the group, oarsman Buck Simmons, is also winning the favor of Aida Courtlandt, the dean's niece, the jealous Browning and gambler Burton Hampdon, to whom Browning owes money, attempt to disgrace Buck so he will not be allowed to participate in the upcoming Yale-Harvard race. After they fail to lure Buck to bed with a girl, Browning takes Aida to a roadhouse so that Buck will have to break training rules to go there. When the coach, suspicious about the roadhouse incident, finds a letter planted on Buck about a deal for him to throw the race, he suspends Buck, but with Aida's influence, the dean straightens matters out. After Yale wins a close race, Browning shoots at Buck, who then trounces him. Proclaimed captain of the next year's team, Buck becomes engaged to Aida.