While delivering an apocalyptic message to his sect, the unearthly Black Jesus orders his leather-clad, biker converts to destroy the pagan mistress Damselvis before she can raise her father, the fabled rock and roll deity Helvis, from the dead. When a sheltered, country schoolgirl named Isla M. (Sherry Lynn Garris) is nearly butchered by Black Jesus’ murderous disciple Candy (Ghetty Chasun), she is miraculously reborn as the fringe-adorned, Harley riding Damselvis; who promptly embarks on a pilgrimage to Memphis, spreading the gospel along the way by disseminating Helvis records to a burgeoning and ardent congregation of fans. Once Helvis is resurrected from his pyramid tomb, he must confront the monstrous Woofman in a final battle to the death to determine the religious rites for the new millennia!

When a lab assistant steals an important formula and all its documentation from Dr. Whitman, he hires a bottom-of-the-barrel private eye, Chase Barr, to locate it. When Barr digs deeper into the case he finds the lab assistant is actually a dead sex worker named Dawn and the "formula" is a reanimation agent that, with the consumption of human blood, is keeping her alive.