Two men wake up to find themselves shackled in a grimy, abandoned bathroom. As they struggle to comprehend their predicament, they discover a disturbing tape left behind by the sadistic mastermind known as Jigsaw. With a chilling voice and cryptic instructions, Jigsaw informs them that they must partake in a gruesome game in order to secure their freedom.

The chilling and relentless Jigsaw killer returns to terrorize the city once again. When a gruesome murder victim emerges with unmistakable traces of Jigsaw's sinister methods, Detective Eric Matthews is thrust into a high-stakes investigation. To his surprise, apprehending Jigsaw seems almost too easy, but what he doesn't realize is that being caught is merely another piece of Jigsaw's intricate puzzle.

Jigsaw has disappeared. Along with his new apprentice Amanda, the puppet-master behind the cruel, intricate games that have terrified a community and baffled police has once again eluded capture and vanished. While city detectives scramble to locate him, Doctor Lynn Denlon and Jeff Reinhart are unaware that they are about to become the latest pawns on his vicious chessboard.

After getting fired from his teaching job and dumped by his girlfriend, Jack, a painter, embarks on a soul searching road trip with his dog, Scout. However, bad weather and bumps in the road quickly cause more problems than he can handle. An impulsive decision to take from a bag full of unknown pills leads him on a drug-fueled journey with no destination in sight, and he soon finds himself making both friends and foes along the way.

A single young woman moves to Los Angeles, gets a job as a chef and has casual affairs.

Jake Kimble, the sole survivor of the Chicago massacre, is killed while in solitary confinement. His doctor begins investigating the claims he made about a long-haired woman in white, as a mysterious Japanese woman arrives at his old apartment building to help them get rid of the curse.

Diane Walters, an over-burdened mother of two with a third child on the way, strives to create the perfect Christmas while her loving but dysfunctional family falls apart around her.

When Doug's father, an Air Force Pilot, is shot down by MiGs belonging to a radical Middle Eastern state, no one seems able to get him out. Doug finds Chappy, an Air Force Colonel who is intrigued by the idea of sending in two fighters piloted by himself and Doug to rescue Doug's father after bombing the MiG base.

Special Agent Strahm is dead, and Detective Hoffman has emerged as the unchallenged successor to Jigsaw's legacy. However, when the FBI draws closer to Hoffman, he is forced to set a game into motion, and Jigsaw's grand scheme is finally understood.

Harry Crumb is a bumbling and inept private investigator who is hired to solve the kidnapping of a young heiress which he's not expected to solve because his employer is the mastermind behind the kidnapping.