A day in the life of a Chicago cab driver is examined as he picks up fares from the good and bad parts of the city and emotionally connects to many of his passengers.

When Sophie's son, Garrett, develops a mysterious illness, she embarks on a search for answers. This leads her into the controversial world of Genetically Modified Organisms (GMOs) where a sociopolitical battle rages between organic farmers and big biotech corporations. As her desperation grows, so too does her quest for knowledge. And the deeper she goes, a more heightened sense of danger develops that preys on her state of mind, as she attempts to discover the root cause of her son's illness.

A young black man searches for his identity in the aftermath of a fatal shooting in South Side, Chicago.

A Chicago weather man, separated from his wife and children, debates whether professional and personal success are mutually exclusive.

Two high school enemies, uber-jock Harry and out-and-proud Sam, are forced to share a car ride to their Missouri hometown for a friend's engagement party on Valentine's Day. Things take a turn when Sam learns Harry has come out.

When the last factory in a small Rust Belt town closes its doors, an unlikely hero emerges in dutiful, quiet Allery Parkes. A career employee of the factory, the aging Allery can't reconcile how to live a life simply sitting at home doing nothing. Against the advice and pleas of his loving wife Iola, he forms an unlikely friendship with his charismatic neighbor Walter Brewer in order to revive the defunct factory.

A distant, slightly dysfunctional family is brought closer together when the father's long-estranged Uncle Nino comes from Italy to Chicago for a surprise visit.

Convinced he'll graduate with honors because of his thesis paper, a stuffy Harvard student finds his paper being held hostage by a homeless man, who might be the guy to school the young man in life.